Author Archives: rcb

High resolution structural and functional analysis of a hemopexin motif protein from Dolichos

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The high-resolution crystal structure of DC25, a 2S albumin protein from Dolichos, at 1.28 Å resolution is reported. The protein has β-propeller structure with a central channel containing only water molecules while the proteins having similar folds have ions along with water or ions only. The four conserved water molecules were found between the blades […]

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DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells

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Uncontrolled inflammation in the gut is one of the major cause for development of inflammatory bowel disease (IBD), a chronic form of autoimmune disorder. Ulcerative colitis (UC) and Crohn’s disease (CD) are the two common forms of IBD involving intestinal distress with varied manifestations resulting in severely compromised patient lifestyles. More importantly in the recent […]

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Molecular Approaches for Analysis of Drosophila MicroRNAs

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MicroRNAs (miRNAs) belong to a class of small non-coding endogenous RNAs that regulate gene expression at the post-transcriptional level. These small RNAs recognize sequences within 3′ untranslated regions of target mRNAs in complexes referred to as a miRNA-induced silencing complex (miRISC). Drosophila melanogaster has served as an indispensable model system for defining the diverse biological roles of […]

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Genome Sequence of a Potential Plant Growth-Promoting Rhizobacterium, Pseudomonas sp. Strain CK-NBRI-02

Pseudomonas sp. strain CK-NBRI-02 is a potential plant growth-promoting Gram-negative rhizobacterium isolated from the rhizosphere of maize plants growing in fields in Srinagar, Jammu, and Kashmir, India. Here, we report a 5.25-Mb draft assembly of the genome sequence of Pseudomonas sp. strain CK-NBRI-02(or P2; GenBank ID: VSJH00000000) with an average G+C content of 62.47%. Deeper analysis of its genome […]

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Detection of Phytopathogenic Fungal strains

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Phytopathogens infect a large number of economically important plants resulting in massive yield loss globally. The effective and early detection strategy is the first measure to control the disease outbreak. Currently, the diagnosis of phytopathogenic fungus relies on traditional staining and culture techniques, however, they face major limitations such as – need to culture the […]

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