Daily Archives: January 18, 2019

Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation.

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 In this study, we have shown that microRNAs (miRNAs) released from the activated microglia upon Japanese Encephalitis virus (JEV) infection may exacerbate CNS damage. We have provided evidence that let-7a and let-7b (let-7a/b secrete through the vesicles from microglial cells in response to JEV infection and induces caspase activation in the primary cortical neurons that are […]

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Salt an Essential Nutrient: Advances in Understanding Salt Taste Detection Using Drosophila as a Model System.

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    Tree of Taste: Taste buds on a human tongue connect to brain and brain decides whether food is palatable or not. Similarly, small insects like Drosophila (fruit fly) has taste buds too. They have hair like structure called sensillum that contain taste neurons (green- leaf like shape) present on the fly mouth and […]

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