Methylation of genomic DNA can influence the transcription profile of an organism and may generate phenotypic diversity for rapid adaptation in a dynamic environment. M.HpyAXI is a type III DNA methyltransferase present in Helicobacter pylori and is upregulated at low pH. This enzyme may alter the expression of critical genes to ensure the survival of […]

As part of collaborative research Dr. Geetanjali Chawla participated in a study that examined the metabolic remodeling that occurs in macrophages during bacterial infection.  This work has revealed that orthologs of Hypoxia inducible factor 1a (HIF1a) and Lactate dehydrogenase (LDH) are required for macrophage activation, bactericidal function of the immune cells and resistance to infection, […]

The rapidly An opinion article by Dr. Geetanjali Chawla discusses the current status of research in the biology of aging in India and some initiatives that can help India to participate more effectively in the field of aging research and deal with the challenges of the rapidly increasing older population. Full article:  https://medwinpublishers.com/JERHA/JERHA16000105.pdf