Category: Science News@RCB

New insights about pilus formation in a probiotic bacterium

Bacterial attachment to the host surfaces is the first and key step in colonization, which may harm or benefit the host based on the natureof host-microbial relationship. Bacteria often assemble and use hair-like organelles known as pili or fimbriae on their cell surface to quickly and effectively mediate attachment. This initial recognition between the bacteria […]

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Antibiotics kill bacteria through induction of reactive oxygen species

Antimicrobial resistance represents a global health problem of escalating intensity. In order to develop new therapeutic strategies, it is important to understand- in fine molecular detail- how antimicrobial agents such as antibiotics achieve function. In the past few years, it has been suggested that antibiotics function through induction of reactive oxygen species (ROS) that damage […]

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Dr. Deepak T. Nair wins the National Bioscience Award, 2014

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Dr. Deepak T. Nair, Associate Professor at the Regional Centre for Biotechnology (RCB), has been awarded the National Bioscience Award for Career Development 2014. The Department of Biotechnology, Government of India, awards this prize to young Indian scientists below 45 years of age to recognize ground breaking research contributions in basic and applied research. Dr. […]

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Salmonella Wrestles with host SUMO

Dr. C. V. Srikanth and his team, identify¬†novel pathway used by intestinal pathogen, SalmonellaTyphimurium, for its infection and survival. Read his recently published findings: http://mcb.asm.org/content/early/2015/06/16/MCB.00397-15.abstract In this work the authors have demonstrated a vital role for SUMOylation, a form of Post Translational Modifications (PTMs) in modulating Salmonella infection. The most unexpected finding here was how […]

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