Author Archives: IT RCB

TLE4 regulates muscle stem cell quiescence and differentiation.

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Our skeletal muscle has an extraordinary capability to regenerate following muscle damage due to injury or disease. A muscle resident pool of stem cells known as satellite cells are essential for skeletal muscle regeneration. Under normal conditions (homeostasis), the satellite cells remain largely dormant (quiescent), but get activated upon muscle injury, leading them to divide […]

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Red seaweed-derived formulations enhance anti‑bacterial defenses in Arabidopsis thaliana and rice

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Every year, huge losses in agriculturally important crops occur due to bacterial pathogen infestations. Due to their broad-spectrum anti-microbial activity, application of seaweed extracts (SWEs) demonstrate high potential as a viable environment-friendly crop loss prevention method. Two extracts from the red algae, Kappaphycus alvarezii, Tomatough® (LBD3) and AgFort® (LBD 12) were developed (by Sea6 Energy […]

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Food Regime for Phenylketonuria: Presenting Complications and Possible Solutions

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This review article highlights current diet therapies available for treatment of a rare genetic disorder, phenylketonuria which has grown to be prevalent in all parts of the world based on numerous epidemiological surveys. This disease is characterized by defective phenylalanine ammonia lyase leading to toxic accumulation of phenylalanine in the blood as well as blood […]

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Phosphate –defense balance

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Role of inositol polyphosphates (InsPs) InsP6, InsP7 and InsP8 in maintaining the phosphate homeostasis is increasingly being established. Additionally, it is reported that phosphate uptake is accompanied by suppression of immune responses to aid colonization of Pi-remobilizing bacteria. Here, we show that Arabidopsis thaliana InsP-kinases IPK1, ITPK1 and VIH2 in addition to maintaining phosphate homeostasis, […]

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SUMO news: Antagonistic crosstalk among Arabidopsis SUMO isoforms in immune balances/trigger

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Plants have been endowed with the ability to tolerate diverse external stress. Several proteins that have been discovered to play a critical part in this adaptation respond quickly to the environmental cues. Post-translational modifications on proteins provide capacity to regulate their functions/fates. This study investigated SUMOylation, the covalent attachment of Small Ubiquitin like modifiers (SUMO) […]

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