Monthly Archives: December 2018

Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis viruses

Potential target for developing anti-viral drugg Amrita Ojha et al. described how the elevated level of a platelet cytokine, PF4 enhanced the replication and infection of Dengue and Japanese Encephalitis (JE) in patients and in mice. They have described that the treatment with AMG487, a small molecule antagonist to CXCR3 (the receptor of PF4) abrogated […]

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