• Welcome

    The RCB blog has been created to share views, thoughts and opinions on education, research, training and events happening at and pertinent to RCB. All RCB members are invited to contribute to the blog by writing articles, sharing recent activities and posting comments. You can send your entries to blog@rcb.res.in

    Arrow
    Arrow
    RCB's first PhD student successfully defended Viva Voce - February 2017
    Slider


Structural basis of probiotic LGG adhesion to the gut

Post Image

Use of antibiotics is not only developing resistance but also destroying the gut microbiota that we earned since birth. Hence the search for alternative approaches including the use of probiotics is being explored. The probiotics are well known for their beneficial effects, including inhibition of colonization by harmful microbes. One of the vital criteria in […]

Share
Read more

Orai3: Oncochannel with therapeutic potential

Post Image

Ion channels in particular Calcium (Ca2+) channels play a critical role in physiology by regulating plethora of cellular processes ranging from cell proliferation, differentiation, transcriptional regulation and programmed cell death. One of the most ubiquitous and highly regulated cellular Ca2+ influx pathways is Store Operated Calcium Entry (SOCE) mediated by Orai1-3 channels. Orai channels are […]

Share
Read more

The proofreading activity of Pfprex from Plasmodium falciparum can prevent mutagenesis of the apicoplast genome by oxidized nucleotide

Post Image

The DNA polymerase module of the Pfprex enzyme (PfpPol) is responsible for duplication of the genome of the apicoplast organelle in the malaria parasite. We show that PfpPol can misincorporate oxidized nucleotides such as 8oxodGTP opposite dA. This event gives rise to transversion mutations that are known to lead to adverse physiological outcomes. The apicoplast […]

Share
Read more

Salivary proteome signatures in the early and middle stages of human pregnancy with term birth outcome

Post Image

Present prospective study is designed to find changes in salivary protein expressions from early to middle phase of term pregnancy. To date, a comprehensive characterization of the longitudinal salivary proteome in pregnancy has not been performed, and here first time we establish an expressional trajectory for modulated proteins in pregnancy. The label free proteomics (SWATH-MS) […]

Share
Read more

Transgelin-2 and phosphoregulation of the LIC2 subunit of dynein regulate mitotic spindle orientation

Post Image

Most cells divide through a highly dynamic but tightly regulated process known as mitosis to help the body grow and develop properly. Mistake(s) during mitosis lead to aberrant growth and development, and often to deadly diseases like cancer. One key event early during mitosis is the proper positioning and orientation of the mitotic spindle within […]

Share
Read more