Dr. Deepti’s group shows that deletion of glycosyl transferase in Pseudomonas aeruginosa results in susceptibility to antibiotics and reduction in biofilms

Bacteria are versatile organisms that instantly respond to changing environmental signals. Motility in bacteria is mediated by multi-protein complex thread like structure called flagella that allows bacteria to move towards favourable conditions. However, bacteria can also form sessile sedentary surface attached communities embedded in think polysaccharide matrix called biofilms.

A research paper published in the journal “Microbiology” by Dr. Jains’s group shows that deletion of the genes responsible for coding for glycosyl transferases, pslG or pslI can result in drastic reduction in biofilm formation. Additionally, the deletion of the two genes can also result in increased susceptibility to antibiotics.

For full article –  https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.001392