Author Archives: IT RCB

Dual RNA-Seq analysis of Medicago truncatula and the pea powdery mildew Erysiphe pisi uncovers distinct host transcriptional signatures during incompatible and compatible interactions and pathogen effector candidates

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Powdery mildew is a serious fungal disease of legumes. A research article published in Genomics by Dr. Chandran’s group provides novel insights into powdery mildew pathogenesis and host resistance mechanisms.  Dual RNA-Seq was used to simultaneously capture host and pathogen transcriptomes at 1 d post-inoculation of resistant and susceptible Medicago truncatula genotypes with the powdery […]

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Lactate dehydrogenase and GPDH1 cooperatively regulate redox balance during Drosophila larval growth.

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 Drosophila melanogaster larval development is characterized by considerable growth and Lactate dehydrogenase (LDH) is crucial for this process because it helps to maintain redox balance within cells by regenerating NAD+ from NADH.  As part of Dr. Jason Tennessen’s team at Indiana University, Dr. Geetanjali Chawla participated in a study that highlight’s the metabolic flexibility of Drosophila larval […]

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