Rhabdomyosarcoma (RMS) is a soft tissue cancer that occurs predominantly in children and adolescents. RMS tumor cells resemble skeletal muscle cells. However, unlike normal skeletal muscle cells which undergo terminal differentiation, RMS tumor cells do not differentiate. The ability to remain undifferentiated could underlie the tumor-specific properties such as proliferation and metastasis in RMS. In […]

Cell wall-derived oligosaccharides are often generated during pathogen attacks and plant development, and plants sense them as a danger signal and trigger the immune response. However, how these oligosaccharide signals can reinforce or remodel the cell wall by maintaining its integrity which  is not explored in detail. Therefore, this study investigated the role of xylan-derived […]

Bacteria are versatile organisms that instantly respond to changing environmental signals. Motility in bacteria is mediated by multi-protein complex thread like structure called flagella that allows bacteria to move towards favourable conditions. However, bacteria can also form sessile sedentary surface attached communities embedded in think polysaccharide matrix called biofilms. A research paper published in the […]

Oral biofilm or dental plaque is a yellowish sticky layer that grows on the tooth surface. It is a complex microbial biofilm community with over 700 different microbes and a major cause of multiple infections, including infective endocarditis. Its growth begins when certain bacteria called primary colonizers attach to oral tissues and undergo coaggregation. Primary […]

Myosins are proteins essential for fundamental cellular functions such as in cell division, transport and migration. A unique set of myosin proteins are expressed by our skeletal muscle, which form part of the contractile network helping movement and posture maintenance. One such myosin is myosin heavy chain-embryonic (MyHC-embryonic), encoded by the Myh3 gene, which is […]