Author Archives: Poorti Kathpalia

7D, a promising antiviral small molecule drug against dengue

Prof. Prasenjit Guchhait’s lab in Regional Centre for Biotechnology, Faridabad, India, has developed a promising antiviral drug for dengue treatment in collaboration with Dr. Shailendra Asthana’s lab in Translational Health Science and Technology Institute, Faridabad. The study was published recently by Gaur KK and Asuru TR et al in the reputed journal EMBO Molecular Medicine. […]

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Mismatch detection in A family DNA pol

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Figure: (A) Domain organization of ApPol1 (B) Crystal structure of ApPol1 and (C) Computational model of DNA-bound structure of ApPol1. Replication of the genome is carried out high fidelity DNA polymerases in all organisms. The DNA polymerases are classified into seven families among which the A, B, C and D families are composed of high […]

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