Insights into the circulating microRNAs in the plasma of patients with dengue infection

A study was conducted to catalog the miRNAs circulating in the plasma of the patients during dengue infection and identify the miRNAs associated with disease progression. To achieve it, we have used a high-throughput small RNA sequencing approach on plasma samples from dengue patients with varying disease severity and compared the data between the different clinical groups of dengue patients.
Our study gives a global view of miRNA expression in the plasma from dengue patients and provides a precious resource of candidate miRNAs involved in dengue infection and disease progression.

High-Throughput RNA Sequencing Analysis of Plasma Samples Reveals Circulating microRNA Signatures with Biomarker Potential in Dengue Disease Progression. mSystems. 2020 Sep-Oct; 5(5): e00724-20. DOI: 10.1128/mSystems.00724-20